SHOX2 Antibody - N-terminal region

Catalog Number: ASB-ARP33285_P050
Article Name: SHOX2 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP33285_P050
Supplier Catalog Number: ARP33285_P050
Alternative Catalog Number: ASB-ARP33285_P050-25UL,ASB-ARP33285_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Guinea pig, Human, Mouse, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SHOX2
Alternative Names: OG12, SHOT, OG12X
SHOX2 is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 35 kDa
NCBI: 6474
UniProt: O60902
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment.
WB Suggested Anti-SHOX2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 721_B cell lysateSHOX2 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells
Host: Rabbit
Target Name: SHOX2
Sample Type: Human Fetal Brain
Antibody Dilution: 1.0ug/ml
SHOX2 antibody - N-terminal region (ARP33285_P050) in Human 721_B using Western Blot