SIRT1 Antibody - N-terminal region
Catalog Number:
ASB-ARP32386_T100
- Images (4)
| Article Name: | SIRT1 Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP32386_T100 |
| Supplier Catalog Number: | ARP32386_T100 |
| Alternative Catalog Number: | ASB-ARP32386_T100-25UL,ASB-ARP32386_T100-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human SIRT1 |
| Alternative Names: | SIR2, SIR2L1, SIR2alpha |
| SIRT1 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. |
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WB Suggested Anti-SIRT1 Antibody Titration: 0.5ug/ml ELISA Titer: 1:1562500 Positive Control: Human Thymus |
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Host: Rabbit Target Name: SIRT1 Sample Tissue: Human 786-0 Antibody Dilution: 1.0ug/ml |
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Surface Plasmon Resonance Kinetic Characterization of Polyclonal Antibody Affinity. Purified polyclonal antibodies were immobilized on a Protein A/G coated Carterra LSA sensor chip (PAGH200M) at concentrations of 5, and 50 ug/mL in duplicate. Antibodies on the surface were exposed to interaction with peptides sequentially via microfluidic controlled flow at 333nM peptide concentration for kinetic characterization of the binders for affinity and specificity, followed by curve fitting using the Kinetics software. Kd determinations for both concentrations were averaged and results and standard deviation are shown. |
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SIRT1 antibody - N-terminal region (ARP32386_T100) in Human 786-0 using Western Blot |
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