NFYA Antibody - C-terminal region

Catalog Number: ASB-ARP31380_P050
Article Name: NFYA Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP31380_P050
Supplier Catalog Number: ARP31380_P050
Alternative Catalog Number: ASB-ARP31380_P050-25UL,ASB-ARP31380_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NFYA
Alternative Names: HAP2, CBF-A, CBF-B, NF-YA
NFYA is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 37kDa
NCBI: 4800
UniProt: P23511
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human Liver
HumanMuscle
WB Suggested Anti-NFYA Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysateNFYA is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
NFYA antibody - C-terminal region (ARP31380_P050) in Human Jurkat using Western Blot