GRK6 Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP51246
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| Article Name: | GRK6 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP51246 |
| Supplier Catalog Number: | AP51246 |
| Alternative Catalog Number: | ABT-AP51246-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | WB |
| Species Reactivity: | Human, Mouse, Rat |
| Alternative Names: | G protein-coupled receptor kinase 6, G protein-coupled receptor kinase GRK6, GRK6, GPRK6 |
| Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro). |
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