GRB14 Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP51245
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| Article Name: | GRB14 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP51245 |
| Supplier Catalog Number: | AP51245 |
| Alternative Catalog Number: | ABT-AP51245-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, IHC-P, IP, WB |
| Species Reactivity: | Human |
| Alternative Names: | Growth factor receptor-bound protein 14, GRB14 adapter protein, GRB14 |
| Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal. |
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