E2F6 Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP51174
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| Article Name: | E2F6 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP51174 |
| Supplier Catalog Number: | AP51174 |
| Alternative Catalog Number: | ABT-AP51174-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, IHC-P, IP, WB |
| Species Reactivity: | Human, Mouse, Rat |
| Alternative Names: | Transcription factor E2F6, E2F-6, E2F6 |
| Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5-TTTC[CG]CGC-3. Has a preference for the 5-TTTCCCGC-3 E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase. |
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