DLX5 Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP51165
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| Article Name: | DLX5 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP51165 |
| Supplier Catalog Number: | AP51165 |
| Alternative Catalog Number: | ABT-AP51165-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, ICC, IHC-P, IP, WB |
| Species Reactivity: | Human, Mouse |
| Alternative Names: | Homeobox protein DLX-5, DLX5 |
| Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5-TAATTA-3 consensus sequence for DNA-binding. |
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