CTDSP1 Antibody, Rabbit, Polyclonal

Catalog Number: ABT-AP51124
Article Name: CTDSP1 Antibody, Rabbit, Polyclonal
Biozol Catalog Number: ABT-AP51124
Supplier Catalog Number: AP51124
Alternative Catalog Number: ABT-AP51124-100UL
Manufacturer: Abcepta
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Human, Mouse, Rat
Alternative Names: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, Nuclear LIM interactor-interacting factor 3, NLI-IF, NLI-interacting factor 3, Small C-terminal domain phosphatase 1, SCP1, Small CTD phosphatase 1, CTDSP1, NIF3, NLIIF, SCP1
Preferentially catalyzes the dephosphorylation of Ser- 5 within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
Clonality: Polyclonal
NCBI: 58190
UniProt: Q9GZU7