MRCK alpha Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP51062
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| Article Name: | MRCK alpha Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP51062 |
| Supplier Catalog Number: | AP51062 |
| Alternative Catalog Number: | ABT-AP51062-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human, Mouse, Rat |
| Alternative Names: | Serine/threonine-protein kinase MRCK alpha, CDC42-binding protein kinase alpha, DMPK-like alpha, Myotonic dystrophy kinase-related CDC42-binding kinase alpha, MRCK alpha, Myotonic dystrophy protein kinase-like alpha, CDC42BPA {ECO:0000312|EMBL:CAH713361}, KIAA0451 |
| Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates: PPP1R12A, LIMK1 and LIMK2. May play a role in TFRC-mediated iron uptake. |
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