CBR1 Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP51049
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| Article Name: | CBR1 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP51049 |
| Supplier Catalog Number: | AP51049 |
| Alternative Catalog Number: | ABT-AP51049-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, ICC, IHC-P, WB |
| Species Reactivity: | Human |
| Alternative Names: | Carbonyl reductase [NADPH] 1, 15-hydroxyprostaglandin dehydrogenase [NADP(+)], NADPH-dependent carbonyl reductase 1, Prostaglandin 9-ketoreductase, Prostaglandin-E(2) 9-reductase, CBR1, CBR, CRN |
| NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione. |
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