ARHGAP22 Antibody, Rabbit, Polyclonal

Catalog Number: ABT-AP50995
Article Name: ARHGAP22 Antibody, Rabbit, Polyclonal
Biozol Catalog Number: ABT-AP50995
Supplier Catalog Number: AP50995
Alternative Catalog Number: ABT-AP50995-100UL
Manufacturer: Abcepta
Host: Rabbit
Category: Antikörper
Application: ELISA, IHC-P, WB
Species Reactivity: Human, Mouse, Rat
Alternative Names: Rho GTPase-activating protein 22, Rho-type GTPase-activating protein 22, ARHGAP22, RHOGAP2
Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter (By similarity).
Clonality: Polyclonal
NCBI: 58504
UniProt: Q7Z5H3