GNL3L Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP50825
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| Article Name: | GNL3L Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP50825 |
| Supplier Catalog Number: | AP50825 |
| Alternative Catalog Number: | ABT-AP50825-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | WB |
| Species Reactivity: | Human |
| Alternative Names: | Guanine nucleotide-binding protein-like 3-like protein, GNL3L |
| Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP. |
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