SLC4A8/10 Antibody, Rabbit, Polyclonal

Catalog Number: ABT-AP50773
Article Name: SLC4A8/10 Antibody, Rabbit, Polyclonal
Biozol Catalog Number: ABT-AP50773
Supplier Catalog Number: AP50773
Alternative Catalog Number: ABT-AP50773-100UL
Manufacturer: Abcepta
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Human, Mouse, Rat
Alternative Names: Electroneutral sodium bicarbonate exchanger 1, Electroneutral Na(+)-driven Cl-HCO3 exchanger, Solute carrier family 4 member 8, k-NBC3, S4A8
Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
Clonality: Polyclonal
NCBI: 9498
UniProt: Q2Y0W8