CANX Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP50720
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| Article Name: | CANX Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP50720 |
| Supplier Catalog Number: | AP50720 |
| Alternative Catalog Number: | ABT-AP50720-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | WB |
| Species Reactivity: | Human, Mouse, Rat |
| Alternative Names: | Calnexin, IP90, Major histocompatibility complex class I antigen-binding protein p88, p90, CANX |
| Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse. |
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