EFNA2 Antibody, Rabbit, Polyclonal

Catalog Number: ABT-AP50698
Article Name: EFNA2 Antibody, Rabbit, Polyclonal
Biozol Catalog Number: ABT-AP50698
Supplier Catalog Number: AP50698
Alternative Catalog Number: ABT-AP50698-100UL
Manufacturer: Abcepta
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Human, Mouse
Alternative Names: Ephrin-A2, EPH-related receptor tyrosine kinase ligand 6, LERK-6, HEK7 ligand, HEK7-L, EFNA2, EPLG6, LERK6
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis (By similarity).
Clonality: Polyclonal
NCBI: 1943
UniProt: O43921