Functional LAG-3 Antibody, mAb (blocking), Clone: [11E3], Monoclonal
Biozol Catalog Number:
ABT-ADP0015-U0100
Supplier Catalog Number:
ADP0015-U0100
Alternative Catalog Number:
ABT-ADP0015-U0100-100UG
Manufacturer:
Abcepta
Category:
Antikörper
Application:
ELISA, ICC, IHC, IP, WB
Species Reactivity:
Human
Alternative Names:
Lymphocyte Activation Gene-3, FDC Protein, CD223
Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.