Cynomolgus MAdCAM-1 Protein, His Tag, low endotoxin, Unconjugated, Human
Biozol Catalog Number:
ABS-MAM-C52H3-1MG
Supplier Catalog Number:
MAM-C52H3-1mg
Alternative Catalog Number:
ABS-MAM-C52H3-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Monkey
Conjugation:
Unconjugated
The mucosal addressin cell adhesion molecule1 (MAdCAM1) takes a key role in the endothelial adhesion and migration of lymphocytes to sites of inflammation in inflammatory disease. In vitro and in vivo data indicate that blockade of the adhesion molecule mucosal address in cell adhesion molecule (MAdCAM) pathway decreases leukocyte homing to the gut by inhibiting the interaction between MAdCAM and its ligand the alpha4beta7 integrin expressed on lymphocytes. - Proteine/Peptide
