Biotinylated Human Klotho beta / KLB Protein, His Tag, ultra sensitivity (primary amine labeling)
Biozol Catalog Number:
ABS-KLB-H82H3-25UG
Supplier Catalog Number:
KLB-H82H3-25ug
Alternative Catalog Number:
ABS-KLB-H82H3-25UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Biotin
KLB (Klotho Beta) is a Protein Coding gene. Among its related pathways are RET signaling and HIV Life Cycle. GO annotations related to this gene include hydrolase activity, hydrolyzing Oglycosyl compounds and fibroblast growth factor binding. An important paralog of this gene is KL. Klotho Beta is a regulator in multiple metabolic processes, while its role in cancer remains unclear. We found the expression of betaKlotho was downregulated in human hepatocellular carcinoma tissues compared with that in paired adjacent nontumourous liver tissues. Hepatoma cells also showed decreased expression of betaKlotho compared with normal hepatocyte cells. Reintroduction of betaKlotho into hepatoma cells inhibited their proliferation. - Proteine/Peptide
