Monoclonal Antibody to RunX3 (Clone: ABM28D1)

Catalog Number: ABI-10-4053-25
Article Name: Monoclonal Antibody to RunX3 (Clone: ABM28D1)
Biozol Catalog Number: ABI-10-4053-25
Supplier Catalog Number: 10-4053-25
Alternative Catalog Number: ABI-10-4053-25-25UG
Manufacturer: Abeomics
Host: Mouse
Category: Antikörper
Application: FACS, WB
Species Reactivity: Human
Immunogen: A partial length recombinant Runx3 protein (amino acids 100-320) was used as the immunogen for this antibody.
Alternative Names: RUNX3||AML2||CBFA3||PEBP2A3
Runt-related transcription factor 3 (Runx3) forms a heterodimer of alpha and beta subunit and binds to the core of the promoter to regulate the transcription. It plays an important role in tumor suppressor and the gene is frequently deleted or transcriptionally silenced during tumor development. It has multiple isoforms coded by multiple transcript variances.
Clonality: Monoclonal
Clone Designation: [ABM28D1]
NCBI: 864
UniProt: Q13761
Purity: Protein G Chromatography
Form: Purified
Target: Runx3
Application Dilute: Western blot analysis: 2-4 µg/ml, Flowcytometry analysis: 0.5-1 µg/10 6 Cells
Figure-1: Western blot analysis of RunX3. Anti- RunX3 antibody (Clone: ABM28D1) was used at 2 µg/ml on (1) HL-60 and (2) Jurkat lysates.
Figure-2:Intracellular flowcytometry analysis of RunX3 on Raji cells using 0.5 µg/10 6 Cells of Anti-RunX3 (Clone: ABM28D1). Green represent isotype control and red represent Anti RunX3 antibody (Abeomics 10-4053). Goat anti mouse PE conjugated was used as the secondary antibody.
Figure-3:Intracellular flowcytometry analysis of RunX3 on Ramos cells using 0.5 µg/10 6 Cells of Anti-RunX3 (Clone: ABM28D1). Green represent isotype control and red represent Anti RunX3 antibody (Abeomics 10-4053). Goat anti mouse PE conjugated was used as the secondary antibody.