In vivo Grade Recombinant Anti-mouse CD19 Monoclonal Antibody (Clone: 1D3), Rat IgG2a Kappa
Biozol Catalog Number:
ABB-YR0381
Supplier Catalog Number:
YR0381
Alternative Catalog Number:
ABB-YR0381-5MG,ABB-YR0381-5X5MG,ABB-YR0381-1MG
Manufacturer:
ABclonal
Category:
Antikörper
Application:
ELISA, FC, NeA
The 1D3 antibody binds to the mouse CD19 protein, a transmembrane protein expressed in all B lineage cells including mouse plasma cells. CD19 plays two major roles in mouse B cells: it acts as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane, and works within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. CD19 is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for leukemia immunotherapies.
Purity:
>95% Determined by SDS-PAGE
Application Notes:
Applications: ELISA,flow cytometry,neutralization,functional assays such as bioanalytical PK and ADA assays,and those assays for studying biological pathways affected by the mouse CD19 protein. Shipping: Ice Bag
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