Human EGFR Monoclonal Antibody, Endotoxin 0.05 EU/mg
Biozol Catalog Number:
ABB-YR0098
Supplier Catalog Number:
YR0098
Alternative Catalog Number:
ABB-YR0098-4X5MG,ABB-YR0098-5MG
Manufacturer:
ABclonal
Category:
Antikörper
Application:
ELISA, NeA
Immunogen:
Human EGFR
Alternative Names:
ERBB, ERRP, HER1, mENA, ERBB1, PIG61, NISBD2
Nimotuzumab Biosimilar uses the same protein sequences as the therapeutic antibody nimotuzumab.Like cetuximab, nimotuzumab is a humanized monoclonal antibody that binds to the epidermal growth factor receptor (EGFR), a signalling protein that normally controls cell division. In some cancers, this receptor is altered to cause uncontrolled cell division, a hallmark of cancer. These monoclonal antibodies block EGFR and stop the uncontrolled cell division.It has a humanized human-mouse h-R3 heavy chain and a humanized human-mouse h-R3 kappa-chain.Nimotuzumab binds with optimal affinity and high specificity to the extracellular region of EGFR (epidermal growth factor receptor). This results in a blockade of ligand binding and receptor activation. Epidermal growth factor receptor (EGFR) is a key target in the development of cancer therapeutics. EGFR-targeting drugs have been shown to improve response when used with conventional treatments such as radiation therapy and chemotherapy.
In Vivo Grade Recombinant Human IgG1 Kappa Isotype Control Antibody
Application Notes:
Applications: ELISA,neutralization,functional assays such as bioanalytical PK and ADA assays,and those assays for studying biological pathways. ResearchArea: Cancer immunology. Shipping: Ice Bag
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