Integrin alphaV, beta5 (FITC), IgG1, Clone: [2Q1009 P1F6], Mouse, Monoclonal
Artikelnummer:
USB-I7661-37T
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| Artikelname: | Integrin alphaV, beta5 (FITC), IgG1, Clone: [2Q1009 P1F6], Mouse, Monoclonal |
| Artikelnummer: | USB-I7661-37T |
| Hersteller Artikelnummer: | I7661-37T |
| Alternativnummer: | USB-I7661-37T-100 |
| Hersteller: | US Biological |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | FC |
| Immunogen: | Human UCLA P3 cells (lung carcinoma). |
| Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. They exist as heterodimers consisting of alpha and beta subunits. Some alpha and beta subunits exhibit specificity for one another and may be designated as a VLA (very late antigen) member. Heterodimers often preferentially bind certain cell adhesion molecules, or constituents of the ECM. Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions. Applications: Suitable for use in Flow Cytometry. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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