Integrin alphaV, beta3 (MaxLight 650), IgG1, Clone: [2Q880 LM609], Mouse, Monoclonal
Artikelnummer:
USB-I7661-37E-ML650
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| Artikelname: | Integrin alphaV, beta3 (MaxLight 650), IgG1, Clone: [2Q880 LM609], Mouse, Monoclonal |
| Artikelnummer: | USB-I7661-37E-ML650 |
| Hersteller Artikelnummer: | I7661-37E-ML650 |
| Alternativnummer: | USB-I7661-37E-ML650-100 |
| Hersteller: | US Biological |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | FC, IF, IHC, IP |
| Immunogen: | Purified adhesion receptor from the human melanoma cell line M21. |
| MaxLight(TM)650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor(TM)647, DyLight(TM)649, Cy5(TM) and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm), Emission (676nm), Extinction Coefficient 250,000. The integrin family of cell adhesion receptors consists of a least 16 membrane-associated heterodimers, composed of an alpha and beta subunit that associate in a non-covalent manner. The structure and functional diversity of the integrin family are based on the pairing abilities of the alpha and beta subunits. The integrins are involved in vascular proliferation, adhesion and wound repair. AlphaVbeta3 appears to be selectively expressed on growing blood vessels and has been identified as a marker of angiogenic vascular tissue. Applications: Suitable for use in Immunoprecipitation, Immunofluorescence, Flow Cytometry, Immunohistochemistry, Immunocytochemistry and Blocking. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: Effective on 4% paraformaldehyde fixed, frozen tissues and cells. Not effective for immunohistochemical staining of paraffin-embedded tissue sections. Optimal dilutions to be determined by the researcher. Recommended Positive Control: Human myeloma cell lines M21 and MoalphaV Recommended Negative Control: Mo cells (this cell line was derived from M21 but does not express integrin alphaV) Storage and Stability: Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight(TM)650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody. |
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