Interleukin-1 beta (IL-1 beta) BioAssay(TM) ELISA Kit, Rat
Artikelnummer:
USB-143887
Hersteller Artikelnummer:
143887
Alternativnummer:
USB-143887-96
Hersteller:
US Biological
Kategorie:
Kits/Assays
Sandwich ELISA quantitative detection kit for Rat IL-1 beta in cell culture supernates, serum and plasma (heparin, EDTA). The Interleukin 1 family is a group of 11 beta trefoil cytokines.1 Interleukin-1, produced mainly by blood monocytes, mediates the panoply of host reactions collectively known as acute phase response .2 Interleukin-1beta (IL-1beta) is a potent stimulator of bone resorption, and has been implicated in the pathogenesis of high bone turnover and osteoporosis.3 IL-1beta belongs to proinflammatory cytokines, promote cancer cell adhesion and liver metastases by up-regulating the expression of vascular cell adhesion molecule-1 (VCAM-1) on hepatic sinusoidal endothelium (HSE).4 Assay Range: 31.2pg/ml-2000pg/ml Sensitivity: < 1 pg/ml Crossreactivity: There is no detectable cross-reactivity with other relevant proteins. Uniprot ID: Q5BKB0 Entrez Gene ID: 24494 Kit Components: 96-well plate pre-coated with anti-IL-1 beta, Rat Lyophilized recombinant IL-1 beta, Rat standard, 10ng/tube, 2Ea USB Cat No Kit Component 143696 Avidin-Biotin-Peroxidase Complex (ABC), 130ul (1:100 dilution) 143697 Sample diluent buffer, 30ml 143698 Antibody diluent buffer, 12ml 143699 ABC diluent buffer, 12ml 143700 TMB color developing agent, 10ml 143701 TMB stop solution, 10ml Storage and Handling: Store at 4C for 6 months, at -20C for 12 months. Avoid multiple freeze-thaw cycles.
