(R)-Colchicine, CAS [[75520-89-7]] Preis auf Anfrage
Artikelnummer:
TGM-TYD-05344
Hersteller Artikelnummer:
TYD-05344
Alternativnummer:
TGM-TYD-05344-10MG, TGM-TYD-05344-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
(R)-Colchicine is the R-isomer of Colchicine. Colchicine is an orally active alkaloid that serves as an effective microtubule protein inhibitor and disruptor. It inhibits microtubule polymerization with an IC50 of 3 nM and acts as a competitive antagonist of the alpha3 glycine receptor (GlyR). Additionally, Colchicine prevents NSAID-induced small intestinal injury by inhibiting the activation of the NLRP3 inflammasome. It exhibits extensive anti-inflammatory, immunosuppressive, and potent antifibrotic effects, with potential applications in gouty arthritis research.
