NC-002 is a cell-penetrating peptide and functions as an inhibitor of the trypsin-like proteasome (Trypsin-likeproteasome), without affecting the activity of lysosomal cysteine proteases. It is an epoxyketone derivative of Leupeptin. NC-002 enhances the sensitivity of myeloma cells to Bortezomib and Carfilzomib and is utilized in cancer research.
Molekulargewicht:
482.63
CAS Nummer:
[1356828-46-0]
Formel:
C23H42N6O5
Target-Kategorie:
Proteasome
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