TNP-GTP tetrasodium is a fluorescently labeled GTP derivative. It acts as an inhibitor of glutamate dehydrogenase (Ki = 2.7 µM) and serves as an antagonist for purinergic P2X2 and P2X2/3 receptors with IC50 values of 0.4 and 1.2 nM, respectively. Additionally, TNP-GTP tetrasodium inhibits rat soluble guanylyl cyclase (Ki = 1.1 nM).
Target-Kategorie:
Dehydrogenase|||P2X Receptor|||Guanylate cyclase
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