OptoBI-1 is a photochromic, TRPC3/6/7-selective agonist based on a benzimidazole structure, with an EC50 of approximately 0.1 µM for TRPC3 in its active cis conformation. OptoBI-1 can precisely regulate neuronal firing and calcium signaling in endothelial cells, and can be used to study TRPC6-dependent NFAT signaling pathways in mast cells.
Molekulargewicht:
523.67
CAS Nummer:
[2415272-11-4]
Formel:
C32H37N5O2
Target-Kategorie:
TRP/TRPV Channel
T37698
T37698
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