21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11beta-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations inCYP2A21, the gene encoding steroid 21-hydroxylase, and have been used as a biomarker for the detection of 21-hydroxylase deficiencies.
Molekulargewicht:
346.47
Reinheit:
98.68%
CAS Nummer:
[641-77-0]
Formel:
C21H30O4
Target-Kategorie:
Endogenous Metabolite
T36915
T36915
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