Lysine-specific Demethylase Inhibitor (1C) (hydrochloride), CAS [[1234494-75-7]]
Artikelnummer:
TGM-T36627
Hersteller Artikelnummer:
T36627
Alternativnummer:
TGM-T36627-1MG,TGM-T36627-5MG,TGM-T36627-10MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Lysine-specific demethylase inhibitor (1C) (LSD inhibitor (1C)) is an inhibitor of LSD1, a repressive demethylase selective for histone H3 lysine 4 (H3K4).1,2LSD inhibitor (1C) inhibits LSD1 activity by 85.9% when used at a concentration of 10 µM.1It increases the level of H3K4 methylation, including H3K4me1 and H3K4me2 but not H3K9me2 levels, in HCT116 human colon carcinoma cells.2LSD inhibitor (1C) also induces re-expression of the Wnt signaling pathway proteins secreted frizzle-related protein 1 (SFRP1), SFRP4, and SFRP5, as well as the transcription factor GATA5, which are aberrantly silenced in HCT116 cells.
Molekulargewicht:
474.34
CAS Nummer:
[1234494-75-7]
Formel:
C15H40Cl4N8
Target-Kategorie:
Others
T36627
T36627
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