CNS-5161 is a selective, non-competitive NMDA receptor antagonist that is able to displace [3H] MK-801 binding with a Ki of 1.8 nm. CNS-5161 inhibits NMDA receptor-mediated excitatory neurotransmission in both in vitro and in vivo experiments, thereby facilitating the study of neuroprotective mechanisms and related signaling pathways. CNS-5161 is commonly used in neuroscience research to assess excitotoxicity and neuronal survival in model systems, and can be employed in studies of the mechanisms underlying central nervous system disorders.
Molekulargewicht:
351.92
CAS Nummer:
[160754-76-7]
Formel:
C16H18ClN3S2
Target-Kategorie:
NMDAR
T27055
T27055
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten