PCC0105005, CAS [[2921670-99-5]] Preis auf Anfrage
Artikelnummer:
TGM-T214425
Hersteller Artikelnummer:
T214425
Alternativnummer:
TGM-T214425-10MG,TGM-T214425-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
PCC0105005 is a dual-target CGRP Receptor antagonist (IC50 = 1.01 nM) and 5-HT1F Receptor partial agonist (EC50 = 77.91 nM). It demonstrates significant efficacy in rat models of migraine. PCC0105005 significantly reduces the expression of CGRP and c-Fos proteins while inhibiting the phosphorylation levels of ERK and CREB. This compound is useful for migraine research.
