PDE4-IN-30 is a selective PDE4 inhibitor with an IC50 of 2.7 nM for PDE4D2, targeting PDE4 through halogen bonding and metal coordination. It demonstrates at least 67 times greater selectivity for PDE4 compared to other PDE subfamilies and is applicable in research for idiopathic pulmonary fibrosis.
Target-Kategorie:
PDE
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