Lotifazole (F 1686) is a non-steroidal anti-inflammatory drug. At low doses, it specifically inhibits delayed-type hypersensitivity reactions without relying on the prostaglandin synthesis inhibition pathway. At higher doses, Lotifazole significantly alleviates carrageenan-induced paw edema in rats, UV-induced erythema in guinea pigs, and pleurisy. Lotifazole can be utilized in the study of T cell-mediated diseases.
Molekulargewicht:
351.63
CAS Nummer:
[71119-10-3]
Formel:
C12H9Cl3N2O2S
Target-Kategorie:
Others
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