Toyaburgine is an isoquinoline compound with anti-tumor activity. It disrupts the PI3K/AKT/mTOR signaling pathway, causing significant morphological changes and cancer cell death in MIA PaCa-2 cells, while also inhibiting cell migration and colony formation. Toyaburgine shows potential for use in pancreatic cancer research.
Target-Kategorie:
mTOR|||Akt|||PI3K
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