ZJY-54 is an orally active dual inhibitor targeting EGFR/LSD1, with IC50 values of 3.8 nM and 0.6 µM, respectively. It inhibits the proliferation of non-small cell lung cancer cells, induces the accumulation of H3K4me2 and H3K9me2, and suppresses the phosphorylation of EGFR signaling. ZJY-54 exhibits antitumor activity.
Target-Kategorie:
EGFR|||Histone Demethylase
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
