WEHI-3773 is an inhibitor of the interaction between VDAC2 and either BAK or BAX. It prevents BAX-mediated apoptosis (Apoptosis) by blocking the recruitment of BAX to the mitochondria through VDAC2. Conversely, WEHI-3773 promotes BAK-mediated apoptosis (Apoptosis) by limiting VDAC2s inhibitory sequestration of BAK. This compound shows promise for research in the field of cancer therapy.
Target-Kategorie:
Bcl-2 Family|||Apoptosis
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