2-Thenoyltrifluoroacetone (TTFA) is a specific inhibitor of mitochondrial respiratory chain complex II (SQR/SDH) with an IC50 value of 51.5 µM. 2-Thenoyltrifluoroacetone can complex with various metal ions and exhibits cytotoxic and antitumor activity. It possesses anti-Mycobacterium tuberculosis activity and can inhibit the growth of Mycobacterium tuberculosis. 2-Thenoyltrifluoroacetone can be used in mechanistic studies of diseases associated with mitochondrial dysfunction.
Molekulargewicht:
222.18
Reinheit:
97.96%
CAS Nummer:
[326-91-0]
Formel:
C8H5F3O2S
Target-Kategorie:
Mitochondrial Metabolism
Fr13361
Fr13361
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