TdT Antibody / DNA nucleotidylexotransferase, Clone: [DNTT/1453], Mouse, Monoclonal
Artikelnummer:
NSJ-V8536SAF-100UG
Hersteller Artikelnummer:
V8536SAF-100UG
Alternativnummer:
NSJ-V8536SAF-100UG
Hersteller:
NSJ Bioreagents
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
ELISA, IHC-P
Spezies Reaktivität:
Human
Immunogen:
A portion of amino acids 52-192 from the human protein was used as the immunogen for the TdT antibody.
Terminal deoxynucleotidyltransferase (TdT) is a DNA polymerase which catalyzes the addition of deoxyribonucleotides onto the 3 termini of DNA. The human TdT gene maps to chromosome 10q24.1 and encodes a 510 amino acid protein. Human TdT is synthesized as a single chain peptide that elicits a minor preference for incorporation of deoxyribonucleotides over ribonucleotides forming DNA strands. TdT is present in immature thymocytes, some bone marrow cells, transformed pre-B and pre-T cell lines, and leukemia cells.
