Amino acids 150-281 were used as the immunogen for the Drebrin 1 antibody.
Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections. Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS. Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines (By similarity). Involved in memory-related synaptic plasticity in the hippocampus (By similarity). [UniProt]
The stated application concentrations are suggested starting points. Titration of the Drebrin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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