Granzyme B Antibody, Clone: [GZB-1], Mouse, Monoclonal
Artikelnummer:
NSJ-V7638-100UG
Hersteller Artikelnummer:
V7638-100UG
Alternativnummer:
NSJ-V7638-100UG
Hersteller:
NSJ Bioreagents
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC-P, WB
Spezies Reaktivität:
Human
Immunogen:
Amino acids 73-187 were used as the immunogen for the Granzyme B antibody.
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. [UniProt]
