A recombinant human partial protein corresponding to amino acids 3-139 was used as the immunogen for the SERBP1 antibody.
May play a role in the regulation of mRNA stability. Binds to the 3-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation. [UniProt]
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)
Anwendungsbeschreibung:
The stated application concentrations are suggested starting points. Titration of the SERBP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
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