A portion of amino acids 1-185 from the human protein was used as the immunogen for the MIC2 antibody.
MIC2/CD99 is implicated in various cellular processes including homotypic aggregation of T cells, upregulation of T cell receptor and MHS molecules, apoptosis of immature thymocytes and leukocyte diapedesis. It is expressed on the cell membrane of some lymphocytes, cortical thymocytes, granulosa cells of the ovary, most pancreatic islet cells, Sertoli cells of the testis, and some endothelial cells.
