Napsin A Antibody, Clone: [NAPSA/1238], Mouse, Monoclonal

Artikelnummer: NSJ-V2995IHC-7ML
Artikelname: Napsin A Antibody, Clone: [NAPSA/1238], Mouse, Monoclonal
Artikelnummer: NSJ-V2995IHC-7ML
Hersteller Artikelnummer: V2995IHC-7ML
Alternativnummer: NSJ-V2995IHC-7ML
Hersteller: NSJ Bioreagents
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC-P
Spezies Reaktivität: Human
Immunogen: A recombinant fragment corresponding to amino acids 189-299 from the human protein was used as the immunogen for the Napsin A antibody.
Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.
Klonalität: Monoclonal
Klon-Bezeichnung: [NAPSA/1238]
UniProt: O96009
Reinheit: Protein G affinity chromatography
Formulierung: Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*
Antibody Type: Primary Antibody
Application Verdünnung: The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Anwendungsbeschreibung: Optimal dilution of the Napsin A antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.