An amino acid sequence from the middle region of human TNF Receptor-Associated Factor 1 (HQSQLDRERILSLEQR) was used as the immunogen for this TRAF1 antibody.
TNF Receptor-Associated Factor 1, also called EBI6, is a protein that in humans is encoded by the TRAF1 gene. The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. Siemienski et al.(1997) used fluorescence in situ hybridization to map the gene to 9q33-q34. Mosialos et al.(1995) found that LMP1, the EBV-transforming protein, specifically associates with LAP1 (TRAF3) or TRAF1 in B lymphoblasts. LMP1 expression redirects LAP1 and TRAF1 from scattered cytoplasmic structures to LMP1 plasma membrane patches. Both LAP1 and TRAF1 associated with the cytoplasmic domain of p80/TNFR2 in vivo.
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reinheit:
Antigen affinity
Formulierung:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Antibody Type:
Primary Antibody
Application Verdünnung:
Western blot: 0.5-1ug/ml
Anwendungsbeschreibung:
The stated application concentrations are suggested starting amounts. Titration of the TRAF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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