A portion of amino acids 10-39 from the human protein was used as the immunogen for the Phospholipase D2 antibody.
Phosphatidylcholine (PC)-specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.[OMIM]
The stated application concentrations are suggested starting points. Titration of the Phospholipase D2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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