Complement factor H Antibody / CFH, Rabbit, Polyclonal
Artikelnummer:
NSJ-F54343-0.08ML
Hersteller Artikelnummer:
F54343-0.08ML
Alternativnummer:
NSJ-F54343-0.08ML
Hersteller:
NSJ Bioreagents
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, IHC-P, WB
Spezies Reaktivität:
Human
Immunogen:
A portion of amino acids 751-780 from the human protein was used as the immunogen for the Complement factor H antibody.
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
The stated application concentrations are suggested starting points. Titration of the Complement factor H antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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