A portion of amino acids 536-564 from the human protein was used as the immunogen for the GTPBP2 antibody.
GTP-binding proteins, or G proteins, constitute a superfamily capable of binding GTP or GDP. G proteins are activated by binding GTP and are inactivated by hydrolyzing GTP to GDP. This general mechanism enables G proteins to perform a wide range of biologic activities.
The stated application concentrations are suggested starting points. Titration of the GTPBP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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