A portion of amino acids 16-50 from human FAM125A was used as the immunogen for the FAM125A antibody.
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down- regulation of EGF receptor. [UniProt]
The stated application concentrations are suggested starting points. Titration of the FAM125A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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