A portion of amino acids 641-674 from human MYPT1 was used as the immunogen for the MYPT1 antibody.
Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity. [UniProt]
The stated application concentrations are suggested starting points. Titration of the MYPT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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